Tempe consumption modulates fecal secondary bile acids, mucins, immunoglobulin A, enzyme activities, and cecal microflora and organic acids in rats.
The present study investigated the effect of dietary tempe, a fermented soy product, on the colonic environment of rats fed high-fat (HF, 30 % fat; experiment 1) or low-fat (LF, 6 % fat; experiment 2) diets. Growing male rats were fed the experimental diets with or without 25 % tempe for 21 days. Te...
| Publicado en: | Plant Foods for Human Nutrition Vol. 68; no. 2; pp. 177 - 184 |
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| Autores principales: | , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Jun2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104074145&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104074145 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09219668 KRL jtl: Plant Foods for Human Nutrition issn: 09219668 maglogo: N pubinfo: dt: Jun2013 vid: 68 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104074145 NLM23645422 2012128636 10.1007/s11130-013-0357-x NLM23645422 104074145 ppf: 177 ppct: 7 formats: tig: atl: Tempe consumption modulates fecal secondary bile acids, mucins, immunoglobulin A, enzyme activities, and cecal microflora and organic acids in rats. aug: au: Utama, Zaki Okazaki, Yukako Tomotake, Hiroyuki Kato, Norihisa affil: Graduate School of Biosphere Science, Hiroshima University, 1-4-4, Higashi-Hiroshima, 739-8528, Japan. sug: subj: Bile Acids and Salts Metabolism Cecum Microbiology Enzymes Metabolism Feces Microbiology Proteins Metabolism Soy Foods Acetic Acid Metabolism Animals Gram-Negative Anaerobic Bacteria Drug Effects Butyric Acids Metabolism Cecum Drug Effects Clostridium Drug Effects Diet Adverse Effects Eating Drug Effects Feces Immunoglobulins Metabolism Steroids Metabolism Male Propionates Metabolism Rats Acids, Acyclic Metabolism Weight Gain Drug Effects Male ab: The present study investigated the effect of dietary tempe, a fermented soy product, on the colonic environment of rats fed high-fat (HF, 30 % fat; experiment 1) or low-fat (LF, 6 % fat; experiment 2) diets. Growing male rats were fed the experimental diets with or without 25 % tempe for 21 days. Tempe consumption slightly but significantly increased the growth of rats fed both the HF and LF diets (P < 0.05). With both the HF and LF diets, dietary tempe markedly reduced a harmful fecal secondary bile acid, lithocholic acid (a risk factor of colon cancer) (P < 0.05), and markedly elevated fecal mucins (indices of intestinal barrier function) and immunoglobulin A (IgA, an index of intestinal immune function) (P < 0.05). With the HF diet, dietary tempe increased cecal acetate, butyrate, propionate, and succinate concentrations (P < 0.05). Analysis of the profile of cecal microflora revealed lower Bacteroides and higher Clostridium cluster XIVa levels in the tempe group of rats fed the HF diet (P < 0.05). Compared with the control group, the fecal activity of β-glucosidase was markedly higher in the tempe group (P < 0.05), while that of urease was lower (P < 0.05) with both the HF and LF diets. The present results suggest that tempe consumption modulates the colonic environment in rats. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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