Virus-like particles containing the tetrameric ectodomain of influenza matrix protein 2 and flagellin induce heterosubtypic protection in mice.

The ectodomain of matrix protein 2 (M2e) is highly conserved among influenza A viruses and can be a promising candidate antigen for a broadly cross-protective vaccine. In this study, a tetrameric M2e (tM2e) and a truncated form of flagellin (tFliC) were coincorporated into virus-like particles (VLPs...

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Detalles Bibliográficos
Publicado en:BioMed Research International Vol. 2013; pp. 686549 - 686550
Autores principales: Wang, Li, Wang, Ying-Chun, Feng, Hao, Ahmed, Tamanna, Compans, Richard W, Wang, Bao-Zhong
Formato: research Journal Article
Publicado: Wiley-Blackwell 2013
Acceso en línea:Ver este registro en EBSCOhost