Hedgehog signal inhibitors suppress the invasion of human rhabdomyosarcoma cells.

Purpose: In the treatment of rhabdomyosarcoma (RMS), invasion and metastasis remain the most critical determinants of resectability and survival. The objective of this study was to determine whether Hedgehog (Hh) signaling plays a role in the invasion of RMS.Methods: Two kinds of specific Hh signali...

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Publicado en:Pediatric Surgery International Vol. 29; no. 11; pp. 1153 - 1159
Autores principales: Oue, Takaharu, Uehara, Shuichiro, Yamanaka, Hiroaki, Nomura, Motonari, Usui, Noriaki
Formato: research Journal Article
Publicado: Springer Nature Nov2013
Acceso en línea:Ver este registro en EBSCOhost