A C. elegans Screening Platform for the Rapid Assessment of Chemical Disruption of Germline Function.

Background: Despite the developmental impact of chromosome segregation errors, we lack the tools to assess environmental effects on the integrity of the germline in animals. Objectives: We developed an assay in Caenorhabditis elegans that fluorescently marks aneuploid embryos after chemical exposure...

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Bibliographic Details
Published in:Environmental Health Perspectives Vol. 121; no. 6; pp. 717 - 725
Main Authors: Allard, Patrick, Kleinstreuer, Nicole C., Knudsen, Thomas B., Colaiácovo, Monica P.
Format: pictorial research tables/charts Journal Article
Published: National Institute of Environmental Health Sciences Jun2013
Online Access:View this record in EBSCOhost