The Relationship Between Grey-Matter and ASD and ADHD Traits in Typical Adults.

We tested whether in 85 healthy adults (18-29 years) there is a relationship between grey-matter (GM) volume and autism and ADHD symptom severity. The structural MRI findings and autism and ADHD self-reports revealed that autism and ADHD symptom severity was correlated with GM volume in the left inf...

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Detalles Bibliográficos
Publicado en:Journal of Autism & Developmental Disorders Vol. 43; no. 7; pp. 1630 - 1642
Autores principales: Geurts, Hilde, Ridderinkhof, K., Scholte, H.
Formato: pictorial research tables/charts Journal Article
Publicado: Springer Nature Jul2013
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:We tested whether in 85 healthy adults (18-29 years) there is a relationship between grey-matter (GM) volume and autism and ADHD symptom severity. The structural MRI findings and autism and ADHD self-reports revealed that autism and ADHD symptom severity was correlated with GM volume in the left inferior frontal gyrus. Autism symptom-severity was correlated with the left posterior cingulate, ADHD with the right parietal lobe, right temporal frontal cortex, bilateral thalamus, and left hippocampus/amygdala complex. Symptom severity of both disorders form a continuum extending into the general population, but it seems to be an oversimplification to typify psychiatric disorders such as autism and ADHD solely as extremes of brain structure abnormalities.