Role of urea in intestinal barrier dysfunction and disruption of epithelial tight junction in chronic kidney disease.
Background: Chronic kidney disease (CKD) impairs intestinal barrier function which leads to endotoxemia and systemic inflammation. We have found depletion of intestinal epithelial tight junction (TJ) proteins in animals with CKD. We further showed that addition of end-stage renal disease patients' p...
| Published in: | American Journal of Nephrology Vol. 37; no. 1; pp. 1 - 7 |
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| Main Authors: | , , |
| Format: | research Journal Article |
| Published: |
Karger AG
Feb2013
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| Online Access: | View this record in EBSCOhost |