Role of urea in intestinal barrier dysfunction and disruption of epithelial tight junction in chronic kidney disease.
Background: Chronic kidney disease (CKD) impairs intestinal barrier function which leads to endotoxemia and systemic inflammation. We have found depletion of intestinal epithelial tight junction (TJ) proteins in animals with CKD. We further showed that addition of end-stage renal disease patients' p...
| Publicado en: | American Journal of Nephrology Vol. 37; no. 1; pp. 1 - 7 |
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| Autores principales: | , , |
| Formato: | research Journal Article |
| Publicado: |
Karger AG
Feb2013
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| Acceso en línea: | Ver este registro en EBSCOhost |