Computational modeling of the human atrial anatomy and electrophysiology.
This review article gives a comprehensive survey of the progress made in computational modeling of the human atria during the last 10 years. Modeling the anatomy has emerged from simple "peanut"-like structures to very detailed models including atrial wall and fiber direction. Electrophysiological m...
| Publicado en: | Medical & Biological Engineering & Computing Vol. 50; no. 8; pp. 773 - 800 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research review Journal Article |
| Publicado: |
Springer Nature
Aug2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104358302&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104358302 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Aug2012 vid: 50 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104358302 NLM22718317 2011623087 10.1007/s11517-012-0924-6 NLM22718317 104358302 ppf: 773 ppct: 27 formats: fmt: @attributes: type: P tig: atl: Computational modeling of the human atrial anatomy and electrophysiology. aug: au: Dössel O Krueger MW Weber FM Wilhelms M Seemann G Dössel, Olaf Krueger, Martin W Weber, Frank M Wilhelms, Mathias Seemann, Gunnar affil: Institute of Biomedical Engineering, Karlsruhe Institute of Technology, Karlsruhe, Germany sug: subj: Action Potentials Physiology Cardiovascular System Physiology Cell Physiology Electrocardiography Methods Heart Conduction System Physiology Models, Biological Animals Computer Simulation ab: This review article gives a comprehensive survey of the progress made in computational modeling of the human atria during the last 10 years. Modeling the anatomy has emerged from simple "peanut"-like structures to very detailed models including atrial wall and fiber direction. Electrophysiological models started with just two cellular models in 1998. Today, five models exist considering e.g. details of intracellular compartments and atrial heterogeneity. On the pathological side, modeling atrial remodeling and fibrotic tissue are the other important aspects. The bridge to data that are measured in the catheter laboratory and on the body surface (ECG) is under construction. Every measurement can be used either for model personalization or for validation. Potential clinical applications are briefly outlined and future research perspectives are suggested. pubtype: Academic Journal doctype: research review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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