Pharmacodynamic evaluation of irinotecan therapy by FDG and FLT PET/CT imaging in a colorectal cancer xenograft model.

Purpose: Longitudinal changes of 3'-[(18) F]fluoro-3'-deoxythymidine (FLT) and 2-deoxy-2-[(18) F]fluoro-D-glucose (FDG) in response to irinotecan therapy in an animal model of colorectal cancer were compared.Procedures: SCID/CB-17 mice with HCT116 tumors were treated with 50 mg/kg irinotecan by intr...

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Publicado en:	Molecular Imaging & Biology Vol. 14; no. 5; pp. 617 - 625
Autores principales:	Mudd SR, Holich KD, Voorbach MJ, Cole TB, Reuter DR, Tapang P, Bukofzer G, Chakravartty A, Donawho CK, Palma JP, Fox GB, Day M, Luo Y, Mudd, Sarah R, Holich, Kimberley D, Voorbach, Martin J, Cole, Todd B, Reuter, David R, Tapang, Paul, Bukofzer, Gail
Formato:	research Journal Article
Publicado:	Springer Nature Oct2012
Acceso en línea:	Ver este registro en EBSCOhost