Fast-specific tomography imaging via Cerenkov emission.
Purpose: Development of more tumor-specific radiopharmaceuticals is not enough; to understand the disease, we must study data modeling. Although fluoro-18-deoxyglucose positron emission tomography can map a multi-peak distribution of trace radioisotopes, optical tomography should also be able to red...
| Publicado en: | Molecular Imaging & Biology Vol. 14; no. 3; pp. 286 - 293 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jun2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104443623&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104443623 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15361632 KJU jtl: Molecular Imaging & Biology issn: 15361632 maglogo: N pubinfo: dt: Jun2012 vid: 14 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104443623 NLM21786071 2011752285 10.1007/s11307-011-0510-6 NLM21786071 104443623 ppf: 286 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Fast-specific tomography imaging via Cerenkov emission. aug: au: Zhong J Qin C Yang X Chen Z Tian J Zhong, Jianghong Qin, Chenghu Yang, Xin Chen, Zhe Yang, Xiang Tian, Jie affil: Intelligent Medical Research Center, Institute of Automation, Chinese Academy of Sciences, Room 931, Automation Building, No.95 Zhongguancun East Road, Beijing, 100190, China sug: subj: Luminescent Measurements Methods Neoplasms Radiography Tomography, X-Ray Computed Methods Animal Studies Computer Simulation Diagnostic Imaging Methods Fludeoxyglucose F 18 Fludeoxyglucose F 18 Diagnostic Use Fludeoxyglucose F 18 Pharmacokinetics Mice Neoplasms Metabolism Radiopharmaceuticals Radiopharmaceuticals Diagnostic Use Radiopharmaceuticals Pharmacokinetics ab: Purpose: Development of more tumor-specific radiopharmaceuticals is not enough; to understand the disease, we must study data modeling. Although fluoro-18-deoxyglucose positron emission tomography can map a multi-peak distribution of trace radioisotopes, optical tomography should also be able to redirect the distribution.Procedures: Multi-view image acquisition of small animals injected with 2-deoxy-2-[(18)F]fluoro-D: -glucose began with X-ray computed tomography scanning and Cerenkov luminescence imaging. After fusion processing, utilization of the geometric row scaling and L (1/2) regularization operator effectively generates in vivo Cerenkov luminescence tomography images with the SP(3) forward model.Results: The identification is confirmed by the comparison between tumor-specific tomography from Cerenkov emission and the radioactivity measured in vitro.Conclusion: The proposed technique can quickly localize the mobility of radionuclides and uptake by organs, which provides an imaging methodology in oncology. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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