Brief Report: Mediation of Treatment Effect in a Communication Intervention for Pre-School Children with Autism.

Tests of mediation in treatment trials can illuminate processes of change and suggest causal influences in development. We conducted a mediation analysis of a previously published randomised controlled trial of parent-mediated communication-focused treatment for autism against ordinary care, with 28...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 42; no. 3; pp. 447 - 455
Autores principales: Aldred, Catherine, Green, Jonathan, Emsley, Richard, McConachie, Helen
Formato: research tables/charts Journal Article
Publicado: Springer Nature Mar2012
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2012
      vid: 42
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      pub: Springer Nature
      place: New York, New York
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        atl: Brief Report: Mediation of Treatment Effect in a Communication Intervention for Pre-School Children with Autism.
      aug:
        au:
          Aldred, Catherine
          Green, Jonathan
          Emsley, Richard
          McConachie, Helen
        affil: Stockport Provider Services, Stockport UK
      sug:
        subj:
          Autism Spectrum Disorder Therapy
          Language Development Education
          Early Childhood Intervention Evaluation
          Parental Role
          Child Development Disorders, Pervasive
          Human
          Child, Preschool
          Videorecording
          Secondary Analysis
          Parent-Child Relations
          Correlation Coefficient
          Interrater Reliability
          Confidence Intervals
          Experimental Studies
          Effect Size
          Teaching Methods
          Scales
          Outcome Assessment
          Analysis of Covariance
          Descriptive Statistics
          Child, Preschool: 2-5 years
      ab: Tests of mediation in treatment trials can illuminate processes of change and suggest causal influences in development. We conducted a mediation analysis of a previously published randomised controlled trial of parent-mediated communication-focused treatment for autism against ordinary care, with 28 children aged 2-5 years (Aldred et al. in J Child Psychol Psychiatr 45:1-11, ). The hypothesised mediating process, targeted by the intervention, was an increase in parental synchronous response within parent-child interaction. The results showed partial mediation, with change in synchrony accounting for 34% of the positive intervention effect on autism symptomatology (Autism Diagnostic Observation Schedule communication and social domain algorithm); the result was confirmed by bootstrap estimation. Improved parental synchronous response to child communication can alter short-term autism symptom outcome with targeted therapy.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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