Comparison of Salivary Cortisol, Serum Cortisol, Plasma ACTH and Urinary Free Cortisol Levels in Thyrotoxic and Hypothyroid Patients.
ABS TRACT Ob jec ti ve: Hypot ha la mo-pi tu i tary-ad re nal (HPA) axis is af fec ted by thyro id hor mo nes. The pre sent study was de sig ned to com pa re the le vel of sa li vary cor ti sol, se rum cor ti sol, plas ma ad - re no cor ti cot ro pic hor mo ne (ACTH) and uri nary fre e cor ti sol (U...
| Publicado en: | Turkiye Klinikleri Journal of Medical Sciences Vol. 32; no. 1; pp. 54 - 59 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Turkiye Klinikleri
Feb2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104544639&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104544639 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13000292 1VOP jtl: Turkiye Klinikleri Journal of Medical Sciences issn: 13000292 maglogo: N pubinfo: dt: Feb2012 vid: 32 iid: 1 pid: 67298 pub: Turkiye Klinikleri artinfo: ui: 104544639 2011503885 10.5336/medsci.2010-22031 104544639 ppf: 54 ppct: 5 formats: fmt: @attributes: type: P tig: atl: Comparison of Salivary Cortisol, Serum Cortisol, Plasma ACTH and Urinary Free Cortisol Levels in Thyrotoxic and Hypothyroid Patients. aug: au: Gönen, Mustafa Sait Özkaya, Emin Kurban, Sevil Ipekci, Süleyman Hilmi Duran, Cevdet Kulaksizoglu, Sevsen affil: Department of Endocrinology, Selçuk University, Meram Faculty of Medicine sug: subj: Adrenocorticotropic Hormone Blood Hydrocortisone Hydrocortisone Blood Hydrocortisone Urine Saliva Thyrotoxicosis Physiopathology Adult Analysis of Variance Chi Square Test Comparative Studies Data Analysis Software Female Human Hypothyroidism Classification Kruskal-Wallis Test Male Middle Age P-Value T-Tests Thyrotoxicosis Classification Thyrotropin Analysis Adult: 19-44 years Middle Aged: 45-64 years Female Male ab: ABS TRACT Ob jec ti ve: Hypot ha la mo-pi tu i tary-ad re nal (HPA) axis is af fec ted by thyro id hor mo nes. The pre sent study was de sig ned to com pa re the le vel of sa li vary cor ti sol, se rum cor ti sol, plas ma ad - re no cor ti cot ro pic hor mo ne (ACTH) and uri nary fre e cor ti sol (UFC) le vels in pa ti ents with subc li - ni cal and overt thyro to xi co sis and hypoth yro i dism. Ma te ri al and Met hods: We analy zed the sa li vary cor ti sol, se rum cor ti sol, plas ma ACTH and UFC le vels in 123 pa ti ents with thyro id dysfunc ti on. The pa ti ents we re clas si fi ed in to fo ur gro ups; overt thyro to xi co sis (n= 32), subc li ni cal thyro to xi co - sis (n= 29), overt hypoth yro i dism (n= 28) and subc li ni cal hypoth yro i dism (n= 34). Re sults: The re we - re no sig ni fi cant dif fe ren ces in terms of sa li vary cor ti sol, se rum cor ti sol, plas ma ACTH and UFC le vels in pa ti ents with subc li ni cal and overt thyro to xi co sis (p> 0.05). Si mi larly, no sig ni fi cant dif - fe ren ces co uld be de tec ted in terms of sa li vary cor ti sol, se rum cor ti sol, plas ma ACTH and UFC le - vels in pa ti ents with subc li ni cal and overt hypoth yro i dism (p> 0.05). The com pa ri son of pa ti ents with hypoth yro i dism and thyro to xi co sis al so did not yi eld any sig ni fi cant dif fe ren ce in terms of sa - li vary cor ti sol, se rum cor ti sol, plas ma ACTH and UFC le vels (p> 0.05). Conc lu si on: Si mi lar sa li vary cor ti sol, se rum cor ti sol, plas ma ACTH and UFC le vels we re de tec ted in pa ti ents with hypoth yro i - dism and thyro to xi co sis. Thus, we may sug gest that thyro id hor mo ne sta tus do es not play a ro le in the HPA axis. The ma jor li mi ta ti on of this study was the ab sen ce of a he althy con trol gro up. Furt - her stu di es with lar ge num bers of pa ti ents are re qu i red to cla rify the as so ci a ti on bet we en thyro id hor mo ne dysfunc ti on and glu co cor ti co id le vels. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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