CYP2D6 genotype and dextromethorphan hydroxylation phenotype in an Ecuadorian population...Cytochrome P450 2D6

Purpose: Cytochrome P450 2D6 ( CYP2D6) genotypes and the dextromethorphan/dextrorphan (DXM/DXT) metabolic ratio (MR), which is a marker of CYP2D6 activity, were studied in 118 unrelated healthy Ecuadorians. Methods: Genotyping of CYP2D6 was performed by amplification of entire CYP2D6 gene by XL-PCR...

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Detalles Bibliográficos
Publicado en:European Journal of Clinical Pharmacology Vol. 68; no. 5; pp. 637 - 645
Autores principales: Dorado, Pedro, Heras, Natalia, Machín, Esther, Hernández, Francisco, Teran, Enrique, LLerena, Adrián
Formato: research tables/charts Journal Article
Publicado: Springer Nature May2012
Acceso en línea:Ver este registro en EBSCOhost