Population pharmacokinetics of metformin in obese and non-obese patients with type 2 diabetes mellitus.

Purpose: The objective of this study was to develop a population pharmacokinetic model and investigate the effect of several demographic covariates on metformin pharmacokinetics in patients with type 2 diabetes mellitus, over a wide range of weights. Methods: A total of 105 patients received differe...

Descripción completa

Detalles Bibliográficos
Publicado en:European Journal of Clinical Pharmacology Vol. 68; no. 6; pp. 961 - 969
Autores principales: Bardin, Christophe, Nobecourt, Estelle, Larger, Etienne, Chast, François, Treluyer, Jean-Marc, Urien, Saik
Formato: equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Jun2012
Acceso en línea:Ver este registro en EBSCOhost