Coronary CT angiography: image quality, diagnostic accuracy, and potential for radiation dose reduction using a novel iterative image reconstruction technique-comparison with traditional filtered back projection.
Objectives: To compare image noise, image quality and diagnostic accuracy of coronary CT angiography (cCTA) using a novel iterative reconstruction algorithm versus traditional filtered back projection (FBP) and to estimate the potential for radiation dose savings.Methods: Sixty five consecutive pati...
| Publicado en: | European Radiology Vol. 21; no. 10; pp. 2130 - 2139 |
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| Autores principales: | , , , , , , , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Oct2011
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104579076&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104579076 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Oct2011 vid: 21 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104579076 65137069 NLM21611758 2011260336 10.1007/s00330-011-2164-9 NLM21611758 104579076 ppf: 2130 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Coronary CT angiography: image quality, diagnostic accuracy, and potential for radiation dose reduction using a novel iterative image reconstruction technique-comparison with traditional filtered back projection. aug: au: Moscariello A Takx RA Schoepf UJ Renker M Zwerner PL O'Brien TX Allmendinger T Vogt S Schmidt B Savino G Fink C Bonomo L Henzler T Moscariello, Antonio Takx, Richard A P Schoepf, U Joseph Renker, Matthias Zwerner, Peter L O'Brien, Terrence X Allmendinger, Thomas affil: Heart & Vascular Center, Medical University of South Carolina, Charleston, SC 29425-2260, USA sug: subj: Coronary Angiography Methods Tomography, X-Ray Computed Methods Adult Aged Algorithms Catheterization Constriction, Pathologic Diagnostic Imaging Female Image Processing, Computer Assisted Methods Male Middle Age Observer Bias Predictive Value of Tests Reproducibility of Results Sensitivity and Specificity Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Objectives: To compare image noise, image quality and diagnostic accuracy of coronary CT angiography (cCTA) using a novel iterative reconstruction algorithm versus traditional filtered back projection (FBP) and to estimate the potential for radiation dose savings.Methods: Sixty five consecutive patients (48 men; 59.3 ± 7.7 years) prospectively underwent cCTA and coronary catheter angiography (CCA). Full radiation dose data, using all projections, were reconstructed with FBP. To simulate image acquisition at half the radiation dose, 50% of the projections were discarded from the raw data. The resulting half-dose data were reconstructed with sinogram-affirmed iterative reconstruction (SAFIRE). Full-dose FBP and half-dose iterative reconstructions were compared with regard to image noise and image quality, and their respective accuracy for stenosis detection was compared against CCA.Results: Compared with full-dose FBP, half-dose iterative reconstructions showed significantly (p = 0.001 - p = 0.025) lower image noise and slightly higher image quality. Iterative reconstruction improved the accuracy of stenosis detection compared with FBP (per-patient: accuracy 96.9% vs. 93.8%, sensitivity 100% vs. 100%, specificity 94.6% vs. 89.2%, NPV 100% vs. 100%, PPV 93.3% vs. 87.5%).Conclusions: Iterative reconstruction significantly reduces image noise without loss of diagnostic information and holds the potential for substantial radiation dose reduction from cCTA. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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