Quantitative texture-based assessment of one-year changes in fibrotic reticular patterns on HRCT in scleroderma lung disease treated with oral cyclophosphamide.

Objectives: The Scleroderma Lung Study showed the efficacy of cyclophosphamide in modestly improving the forced vital capacity (FVC) compared with placebo over 1 year. Using changes in texture-based scores that quantify lung fibrosis as the percentage involvement of reticulation patterns, the effect...

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Bibliographic Details
Published in:European Radiology Vol. 21; no. 12; pp. 2455 - 2466
Main Authors: Kim HJ, Brown MS, Elashoff R, Li G, Gjertson DW, Lynch DA, Strollo DC, Kleerup E, Chong D, Shah SK, Ahmad S, Abtin F, Tashkin DP, Goldin JG, Kim, Hyun J, Brown, Matthew S, Elashoff, Robert, Li, Gang, Gjertson, David W, Lynch, David A
Format: clinical trial research Journal Article
Published: Springer Nature Dec2011
Online Access:View this record in EBSCOhost