High dose ascorbic acid does not reverse central sympathetic overactivity in chronic heart failure.

Summary What is known and Objective: The increased central sympathetic activity typically associated with chronic heart failure (CHF) is probably mediated by formation of reactive oxygen species (ROS) in the brain. Our objective was to undertake a trial to test our hypothesis that administration of...

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Bibliographic Details

Published in:	Journal of Clinical Pharmacy & Therapeutics Vol. 36; no. 5; pp. 546 - 553
Main Authors:	Gomes, M. E., El Messaoudi, S., Lenders, J. W. M., Bellersen, L., Verheugt, F. W. A., Smits, P., Tack, C. J.
Format:	research tables/charts randomized controlled trial Journal Article
Published:	Wiley-Blackwell Oct2011
Online Access:	View this record in EBSCOhost