Postprandial ghrelin and PYY responses of male subjects on low carbohydrate meals to varied balancing proportions of proteins and fats.
PURPOSE: This study was conducted to investigate whether a higher proportion of protein or fat is more favorable for optimal ghrelin and peptide YY (PYY) release in subjects consuming low carbohydrate meals. METHODS: Eight normal weight men received, on three separate occasions, high protein low fat...
| Publicado en: | European Journal of Nutrition Vol. 49; no. 8; pp. 493 - 501 |
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| Autores principales: | , , , |
| Formato: | clinical trial research tables/charts Journal Article |
| Publicado: |
Springer Nature
Dec2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104953328&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104953328 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14366207 CR0 jtl: European Journal of Nutrition issn: 14366207 maglogo: N pubinfo: dt: Dec2010 vid: 49 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104953328 2010869088 10.1007/s00394-010-0108-9 NLM20396896 104953328 ppf: 493 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Postprandial ghrelin and PYY responses of male subjects on low carbohydrate meals to varied balancing proportions of proteins and fats. aug: au: El Khoury, Dalia El-Rassi, Rola Azar, Sami Hwalla, Nahla affil: Department of Nutrition and Food Sciences, Faculty of Agricultural and Food Sciences, American University of Beirut, PO Box 11-0236, Riad El Solh, Beirut, 1107-2020, Lebanon; nahla@aub.edu.lb sug: subj: Diet, Low Carbohydrate Dietary Fats Administration and Dosage Dietary Proteins Administration and Dosage Ghrelin Metabolism Peptides Metabolism Blood Glucose Analysis Body Mass Index Evaluation Body Weights and Measures Calorimetry Crossover Design Data Analysis Software Descriptive Statistics Funding Source Human Insulin Blood Intervention Trials Lebanon Male One-Way Analysis of Variance Pearson's Correlation Coefficient Post Hoc Analysis Triglycerides Blood Two-Way Analysis of Variance Young Adult Male ab: PURPOSE: This study was conducted to investigate whether a higher proportion of protein or fat is more favorable for optimal ghrelin and peptide YY (PYY) release in subjects consuming low carbohydrate meals. METHODS: Eight normal weight men received, on three separate occasions, high protein low fat (HPLF) (40% protein, 25% fat), low protein high fat (LPHF) (10% protein, 55% fat) or medium protein medium fat (MPMF) (25% protein, 40% fat) meals, with equal low carbohydrates content in all three meals (35% of energy). Postprandial blood samples were collected before and 15, 30, 60, 120, 180 and 240 min following the ingestion of each meal. Plasma acylated ghrelin and PYY(3-36) as well as serum insulin, glucose and triglycerides were measured. RESULTS: Comparing meals and considering each time point separately, a trend for a statistically significant difference in acylated ghrelin was observed between HPLF and LPHF meals and a statistically significant change of PYY from baseline was noted between HPLF and LPHF meals as compared to the MPMF meal at certain time points. When data were pooled together, a statistically significant difference in acylated ghrelin change from baseline was observed between HPLF and LPHF meals, while both HPLF and LPHF meals resulted in a significantly higher PYY(3-36) release in comparison to MPMF meal. AUC data analysis for PYY(3-36) revealed significantly higher values following HPLF in comparison to MPMF meal. Correlation analysis revealed a significant negative correlation between acylated ghrelin and insulin only with the HPLF meal. Postprandial glucose and triglyceride levels were not significantly different between the three meals. CONCLUSIONS: In subjects consuming low carbohydrate meals, higher concentrations of proteins to fat seem to have more favorable effects on postprandial appetite hormones. pubtype: Academic Journal doctype: clinical trial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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