Akt-mediated mechanotransduction in murine fibroblasts during hypertrophic scar formation.

Although numerous factors are implicated in skin fibrosis, the exact pathophysiology of hypertrophic scarring remains unknown. We recently demonstrated that mechanical force initiates hypertrophic scar formation in a murine model, potentially enhancing cellular survival through Akt. Here, we specifi...

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Detalles Bibliográficos
Publicado en:Wound Repair & Regeneration Vol. 19; no. 1; pp. 49 - 59
Autores principales: Paterno J, Vial IN, Wong VW, Rustad KC, Sorkin M, Shi Y, Bhatt KA, Thangarajah H, Glotzbach JP, Gurtner GC
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell Jan/Feb2011
Acceso en línea:Ver este registro en EBSCOhost