Akt-mediated mechanotransduction in murine fibroblasts during hypertrophic scar formation.

Although numerous factors are implicated in skin fibrosis, the exact pathophysiology of hypertrophic scarring remains unknown. We recently demonstrated that mechanical force initiates hypertrophic scar formation in a murine model, potentially enhancing cellular survival through Akt. Here, we specifi...

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Bibliographic Details
Published in:Wound Repair & Regeneration Vol. 19; no. 1; pp. 49 - 59
Main Authors: Paterno J, Vial IN, Wong VW, Rustad KC, Sorkin M, Shi Y, Bhatt KA, Thangarajah H, Glotzbach JP, Gurtner GC
Format: pictorial research tables/charts Journal Article
Published: Wiley-Blackwell Jan/Feb2011
Online Access:View this record in EBSCOhost