The pharmacokinetics and pharmacodynamics of prasugrel in healthy Chinese, Japanese, and Korean subjects compared with healthy Caucasian subjects.
Prasugrel is a novel thienopyridine prodrug metabolised to an active metabolite that binds irreversibly to the platelet P2Y12 receptor and inhibits adenosine diphosphate (ADP)-induced platelet aggregation. We compared prasugrel pharmacokinetics, pharmacodynamics, and tolerability in healthy Chinese,...
| Publicado en: | European Journal of Clinical Pharmacology Vol. 66; no. 2; pp. 127 - 136 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | clinical trial equations & formulas research tables/charts Journal Article |
| Publicado: |
Springer Nature
Feb2010
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| Acceso en línea: | Ver este registro en EBSCOhost |