The pharmacokinetics and pharmacodynamics of prasugrel in healthy Chinese, Japanese, and Korean subjects compared with healthy Caucasian subjects.

Prasugrel is a novel thienopyridine prodrug metabolised to an active metabolite that binds irreversibly to the platelet P2Y12 receptor and inhibits adenosine diphosphate (ADP)-induced platelet aggregation. We compared prasugrel pharmacokinetics, pharmacodynamics, and tolerability in healthy Chinese,...

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Bibliographic Details

Published in:	European Journal of Clinical Pharmacology Vol. 66; no. 2; pp. 127 - 136
Main Authors:	Small DS, Kothare P, Yuen E, Lachno DR, Li YG, Winters KJ, Farid NA, Ni L, Jakubowski JA, Salazar DE, Thieu VT, Payne CD
Format:	clinical trial equations & formulas research tables/charts Journal Article
Published:	Springer Nature Feb2010
Online Access:	View this record in EBSCOhost