Histology of Metaplasia and Dysplasia in Barrett's Esophagus.

The histologic diagnosis of Barrett's dysplasia requires the identification of intestinal metaplasia, which often presents a challenge due to sampling error, observer variation, and difficulty in histologic interpretation. Particularly problematic is the separation of negative, indefinite, and low-g...

Descripción completa

Detalles Bibliográficos
Publicado en:Surgical Oncology Clinics of North America Vol. 18; no. 3; pp. 411 - 423
Autor principal: Yerian L
Formato: research Journal Article
Publicado: W B Saunders 2009 Jul
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:The histologic diagnosis of Barrett's dysplasia requires the identification of intestinal metaplasia, which often presents a challenge due to sampling error, observer variation, and difficulty in histologic interpretation. Particularly problematic is the separation of negative, indefinite, and low-grade dysplasia, the varied histological appearances of high-grade dysplasia, and the diagnosis of suboptimal biopsy material. This article seeks to aid in the histological evaluation of metaplasia and dysplasia in Barrett's esophagus. Copyright © 2009 by Elsevier Inc.