Histology of Metaplasia and Dysplasia in Barrett's Esophagus.

The histologic diagnosis of Barrett's dysplasia requires the identification of intestinal metaplasia, which often presents a challenge due to sampling error, observer variation, and difficulty in histologic interpretation. Particularly problematic is the separation of negative, indefinite, and low-g...

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Publicado en:Surgical Oncology Clinics of North America Vol. 18; no. 3; pp. 411 - 423
Autor principal: Yerian L
Formato: research Journal Article
Publicado: W B Saunders 2009 Jul
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2009 Jul
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      pub: W B Saunders
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        10.1016/j.soc.2009.03.011
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        atl: Histology of Metaplasia and Dysplasia in Barrett's Esophagus.
      aug:
        au: Yerian L
        affil: Hepatobiliary and Gastrointestinal Pathology, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA; Department of Anatomic Pathology, Cleveland Clinic, 9500 Euclid Avenue/L25, Cleveland, OH 44195, USA.
      sug:
        subj:
          Barrett Esophagus Pathology
          Esophagus Pathology
          Histological Techniques Methods
          Precancerous Conditions Pathology
          Adenocarcinoma Etiology
          Barrett Esophagus Complications
          Biopsy
          Cell Transformation, Neoplastic Pathology
          Diagnosis, Differential
          Epithelial Cells Pathology
          Esophageal Neoplasms Etiology
          Gastroesophageal Reflux Complications
          Histocytochemistry
          Histological Techniques Standards
          Metaplasia
          Neoplasm Staging
          Observer Bias
          Precancerous Conditions Complications
          Selection Bias
          Severity of Illness Indices
          Human
      ab: The histologic diagnosis of Barrett's dysplasia requires the identification of intestinal metaplasia, which often presents a challenge due to sampling error, observer variation, and difficulty in histologic interpretation. Particularly problematic is the separation of negative, indefinite, and low-grade dysplasia, the varied histological appearances of high-grade dysplasia, and the diagnosis of suboptimal biopsy material. This article seeks to aid in the histological evaluation of metaplasia and dysplasia in Barrett's esophagus. Copyright © 2009 by Elsevier Inc.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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