Growth inhibitory and anti-tumour activities of OSU-03012, a novel PDK-1 inhibitor, on vestibular schwannoma and malignant schwannoma cells.
BACKGROUND: Vestibular schwannomas (VS) frequently express high levels of activated AKT. Small-molecule inhibitors of AKT signalling may have therapeutic potential in suppressing the growth of benign VS and malignant schwannomas. METHOD: Primary VS and Schwann cells, human malignant schwannoma HMS-9...
| Publicado en: | European Journal of Cancer Vol. 45; no. 9; pp. 1709 - 1721 |
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| Autores principales: | , , , , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Pergamon Press - An Imprint of Elsevier Science
Jun2009
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| Acceso en línea: | Ver este registro en EBSCOhost |