Mitochondrial and sarcoplasmic protein changes in hearts from copper-deficient rats: up-regulation of PGC-1alpha transcript and protein as a cause for mitochondrial biogenesis in copper deficiency.

Changes in mitochondrial and sarcoplasmic proteins using proteinomics and Western blotting in hearts from copper-deficient rats were explored in this study. Also, key enzymes that are involved in cardiac energy metabolism via glycolysis and fatty acid oxidation and related transcription factors were...

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Bibliographic Details
Published in:Journal of Nutritional Biochemistry Vol. 20; no. 10; pp. 823 - 831
Main Authors: Medeiros DM, Jiang Y, Klaahsen D, Lin D, Medeiros, Denis M, Jiang, Yu, Klaahsen, Darcey, Lin, Dingbo
Format: research Journal Article
Published: Elsevier B.V. Oct2009
Online Access:View this record in EBSCOhost