Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects.
PURPOSE: Ultrarapid drug metabolism of antidepressants has been associated with therapeutic failures. The CYP2C19*17 allele has been associated with higher levels of CYP2C19 gene transcription and increased rates of omeprazole and mephenytoin metabolism. The aim of this study was to compare the impa...
| Publicado en: | European Journal of Clinical Pharmacology Vol. 64; no. 12; pp. 1175 - 1180 |
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| Autores principales: | , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Dec2008
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| Acceso en línea: | Ver este registro en EBSCOhost |