Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects.

PURPOSE: Ultrarapid drug metabolism of antidepressants has been associated with therapeutic failures. The CYP2C19*17 allele has been associated with higher levels of CYP2C19 gene transcription and increased rates of omeprazole and mephenytoin metabolism. The aim of this study was to compare the impa...

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Bibliographic Details

Published in:	European Journal of Clinical Pharmacology Vol. 64; no. 12; pp. 1175 - 1180
Main Authors:	Rosenborg SO, Mwinyi J, Andersson M, Baldwin RM, Pedersen RS, Sim SC, Bertilsson L, Ingelman-Sundberg M, Eliasson E
Format:	research Journal Article
Published:	Springer Nature Dec2008
Online Access:	View this record in EBSCOhost