Transcript analysis of the selenoproteome indicates that dietary selenium requirements of rats based on selenium-regulated selenoprotein mRNA levels are uniformly less than those based on glutathione peroxidase activity.

Dietary selenium (Se) requirements in rats have been based largely upon glutathione peroxidase-1 (Gpx1) enzyme activity and Gpx1 mRNA levels can also be used to determine Se requirements. The identification of the complete selenoprotein proteome suggests that we might identify additional useful mole...

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Bibliographic Details
Published in:Journal of Nutrition Vol. 139; no. 2; pp. 199 - 207
Main Authors: Barnes KM, Evenson JK, Raines AM, Sunde RA, Barnes, Kimberly M, Evenson, Jacqueline K, Raines, Anna M, Sunde, Roger A
Format: research Journal Article
Published: Elsevier B.V. Feb2009
Online Access:View this record in EBSCOhost