Immunoproteasome in Macaca fascicularis: no age-dependent modification of abundance and activity in the brain and insight into an in silico structural model.

In this study, we investigated proteasome composition and activity in the brain of Macaca fascicularis, in order to test whether this nonhuman primate species might be a suitable animal model for anti-aging therapies in the central nervous system, addressed to the ubiquitin-proteasome system. We det...

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Publicado en:Rejuvenation Research Vol. 11; no. 1; pp. 73 - 83
Autores principales: Bellavista E, Mishto M, Santoro A, Bertoni-Freddari C, Sessions RB, Franceschi C
Formato: research Journal Article
Publicado: Mary Ann Liebert, Inc. Feb2008
Acceso en línea:Ver este registro en EBSCOhost