Differentiating the neural response to intervention in children with developmental dyslexia.

Developmental dyslexia is associated with functional abnormalities within reading areas of the brain. For some children diagnosed with dyslexia, phonologically based remediation programs appear to rehabilitate brain function in key reading areas (Shaywitz et al., Biological Psychiatry 55: 101–110, ;...

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Publicado en:Annals of Dyslexia Vol. 58; no. 1; pp. 1 - 15
Autores principales: Odegard TN, Ring J, Smith S, Biggan J, Black J
Formato: research Journal Article
Publicado: Springer Nature 2008
Acceso en línea:Ver este registro en EBSCOhost
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        07369387
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      jtl: Annals of Dyslexia
      issn: 07369387
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      dt: 2008
      vid: 58
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      pub: Springer Nature
      place: New York, New York
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        105773072
        2009936410
        10.1007/s11881-008-0014-5
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        105773072
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        atl: Differentiating the neural response to intervention in children with developmental dyslexia.
      aug:
        au:
          Odegard TN
          Ring J
          Smith S
          Biggan J
          Black J
        affil: University of Texas at Arlington, Arlington, TX, USA, odegard@uta.edu.
      sug:
        subj:
          Dyslexia Physiopathology
          Dyslexia Rehabilitation
          Neurons Physiology
          Parietal Lobe Physiopathology
          Remedial Teaching
          Adolescence
          Brain Mapping
          Child
          Cross Sectional Studies
          Female
          Magnetic Resonance Imaging
          Male
          Parietal Lobe
          Treatment Outcomes
          Human
          Adolescent: 13-18 years
          Child: 6-12 years
          Female
          Male
      ab: Developmental dyslexia is associated with functional abnormalities within reading areas of the brain. For some children diagnosed with dyslexia, phonologically based remediation programs appear to rehabilitate brain function in key reading areas (Shaywitz et al., Biological Psychiatry 55: 101–110, ; Simos et al., Neuroscience 58: 1203–1213, ). However, a non-trivial number of children diagnosed with dyslexia fail to respond to these interventions (Torgesen, Learning Disabilities Research & Practice 15: 55–64, ). A cross-sectional fMRI study investigating post-treatment effects was conducted in an effort to better understand differences in brain function between treatment responders and non-responders. Educational testing and brain activation measured after treatment suggested that the reading intervention used in the present study rehabilitated several basic level reading processes in all participants diagnosed with dyslexia. However, activation in the left inferior parietal lobe differentiated treatment responders and non-responders in comparison to non-impaired readers. Children with persistent deficits in single word decoding (treatment non-responders) demonstrated significantly less activation in the left inferior parietal lobe when compared to non-impaired readers.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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