Rheumatoid factor and anti-CCP autoantibodies in rheumatoid arthritis: a review.
For many years, laboratory diagnosis of rheumatoid arthritis has relied on the detection of rheumatoid factor. A new assay that detects antibodies to citrullinated peptides, called the anti-CCP assay, has demonstrated a comparable sensitivity but a much higher specificity than the RF test. This pape...
| Publicado en: | Clinical Laboratory Science Vol. 21; no. 1; pp. 15 - 19 |
|---|---|
| Autores principales: | , , |
| Formato: | Journal Article |
| Publicado: |
American Society for Clinical Laboratory Science
Winter2008
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| Sumario: | For many years, laboratory diagnosis of rheumatoid arthritis has relied on the detection of rheumatoid factor. A new assay that detects antibodies to citrullinated peptides, called the anti-CCP assay, has demonstrated a comparable sensitivity but a much higher specificity than the RF test. This paper reviews RF and anti-CCP in rheumatoid arthritis and examines the usefulness of each autoantibody in RA testing. |
|---|