Identification of HLA-B27-restricted peptides in reactive arthritis and other spondyloarthropathies: computer algorithms and fluorescent activated cell sorting analysis as tools for hunting of HLA-B27-restricted chlamydial and autologous crossreactive peptides involved in reactive arthritis and ankylosing spondylitis.
The illustrated clinical and experimental results demonstrate the strong relationship between the MHC class I antigen HLA-B27 and synovial CD8+ T cells with specificity for bacterial and possible self-antigen in SpA. These new aspects obtained in recent experimental and clinical studies might also p...
| Publicado en: | Rheumatic Disease Clinics of North America Vol. 29; no. 3; pp. 595 - 612 |
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| Autores principales: | , |
| Formato: | Journal Article |
| Publicado: |
W B Saunders
2003 Aug
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| Acceso en línea: | Ver este registro en EBSCOhost |