Ecthyma gangrenosum in a patient with toxic epidermal necrolysis.
Toxic epidermal necrolysis and Stevens-Johnson syndrome are a spectrum of disease characterized by a delayed hypersensitivity reaction that involves the skin and mucous membranes and typically is associated with either recent upper respiratory infection or with certain medications. Ecthyma gangrenos...
| Publicado en: | Journal of Burn Care & Research Vol. 28; no. 1; pp. 198 - 203 |
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| Autores principales: | , , , , , , , , , |
| Formato: | case study Journal Article |
| Publicado: |
Oxford University Press / USA
2007 Jan-Feb
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106022149&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106022149 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1559047X 1W56 jtl: Journal of Burn Care & Research issn: 1559047X maglogo: N pubinfo: dt: 2007 Jan-Feb vid: 28 iid: 1 pid: 622 pub: Oxford University Press / USA artinfo: ui: 106022149 106022149 NLM17211226 2009508058 10.1097/bcr.0b013e31802ca481 NLM17211226 106022149 ppf: 198 ppct: 5 formats: tig: atl: Ecthyma gangrenosum in a patient with toxic epidermal necrolysis. aug: au: Downey DM O'Bryan MC Burdette SD Michael JR Saxe JM Downey, Douglas M O'Bryan, Meghan C Burdette, Steve D Michael, Johnson R Saxe, Jonathan M affil: Department of Surgery, Wright State University School of Medicine, Dayton, Ohio, USA sug: subj: Bacteremia Microbiology Pyoderma Complications Epidermal Necrolysis, Toxic Complications Gangrene Microbiology Antiinfective Agents Adverse Effects Debridement Pyoderma Therapy Epidermal Necrolysis, Toxic Therapy Fatal Outcome Female Gangrene Therapy Middle Age Pseudomonas Staphylococcus Aureus Sulfamethoxazole Adverse Effects Trimethoprim Adverse Effects Middle Aged: 45-64 years Female ab: Toxic epidermal necrolysis and Stevens-Johnson syndrome are a spectrum of disease characterized by a delayed hypersensitivity reaction that involves the skin and mucous membranes and typically is associated with either recent upper respiratory infection or with certain medications. Ecthyma gangrenosum is a rare necrotizing vasculitis that most commonly affects immunocompromised and burn patients and is often a sequela of Pseudomonas aeruginosa bacteremia. The cutaneous lesions of ecthyma gangrenosum are characterized by an erythematous halo surrounding a dark gray or black nodule. P. aeruginosa preferentially invades the venules, resulting in secondary thrombosis of the arterioles, tissue edema, and separation of the epidermis. Management of ecthyma gangrenosum includes systemic treatment with antipseudomonal antibiotics and débridment of the lesions, as well as improving the patient's immune status if possible. We present a case of a patient admitted to the burn unit for toxic epidermal necrolysis who developed pseudomonal bacteremia with ecthyma gangrenosum. pubtype: Academic Journal doctype: case study Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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