Giant Blastoconidia of Candida albicans.

We describe a patient with extranodal non-Hodgkin lymphoma who developed systemic candidiasis after treatment with a cyclophosphamide-based chemotherapy regimen. Histologically, the fungal organisms demonstrated markedly enlarged blastoconidia with a variety of morphologic forms, mimicking other myc...

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Detalles Bibliográficos
Publicado en:Archives of Pathology & Laboratory Medicine Vol. 127; no. 7; pp. 868 - 872
Autores principales: Alasio TM, Lento PA, Bottone EJ
Formato: case study Journal Article
Publicado: College of American Pathologists Jul2003
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:We describe a patient with extranodal non-Hodgkin lymphoma who developed systemic candidiasis after treatment with a cyclophosphamide-based chemotherapy regimen. Histologically, the fungal organisms demonstrated markedly enlarged blastoconidia with a variety of morphologic forms, mimicking other mycotic organisms, such as Cryptococcus neoformans, Blastomyces dermatitidis, and Paracoccidioides brasiliensis. The in vivo occurrence of such giant forms is rare, and when observed histologically may result in an erroneous diagnosis or a diagnosis of multiple mycotic organisms.