Giant Blastoconidia of Candida albicans.

We describe a patient with extranodal non-Hodgkin lymphoma who developed systemic candidiasis after treatment with a cyclophosphamide-based chemotherapy regimen. Histologically, the fungal organisms demonstrated markedly enlarged blastoconidia with a variety of morphologic forms, mimicking other myc...

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Bibliographic Details
Published in:Archives of Pathology & Laboratory Medicine Vol. 127; no. 7; pp. 868 - 872
Main Authors: Alasio TM, Lento PA, Bottone EJ
Format: case study Journal Article
Published: College of American Pathologists Jul2003
Online Access:View this record in EBSCOhost
Description
Summary:We describe a patient with extranodal non-Hodgkin lymphoma who developed systemic candidiasis after treatment with a cyclophosphamide-based chemotherapy regimen. Histologically, the fungal organisms demonstrated markedly enlarged blastoconidia with a variety of morphologic forms, mimicking other mycotic organisms, such as Cryptococcus neoformans, Blastomyces dermatitidis, and Paracoccidioides brasiliensis. The in vivo occurrence of such giant forms is rare, and when observed histologically may result in an erroneous diagnosis or a diagnosis of multiple mycotic organisms.