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Focus on... indiplon: a short-acting GABA-A receptor agonist sedative hypnotic for the treatment of insomnia.

A number of clinical approaches are utilized in managing insomnia. Indipion (Pfizer) is a selective non-benzodiazepine sedative hypnotic under consideration by FDA for the treatment of insomnia. Like other agents in its class, indiplon binds selectively to the GABA-A receptors in the brain, promotin...

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Publicado en:Formulary Vol. 41; no. 7; pp. 316 - 321
Autores principales: Gryskiewicz KA, Semanco M
Formato: tables/charts Journal Article
Publicado: MJH Life Sciences Jul2006
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Focus on... indiplon: a short-acting GABA-A receptor agonist sedative hypnotic for the treatment of insomnia.
      aug:
        au:
          Gryskiewicz KA
          Semanco M
        affil: Clinical Pharmacist, Hartford Hospital, Hartford, CT; kgryskiewicz@harthosp.org
      sug:
        subj:
          Insomnia Drug Therapy
          Clinical Trials
          GABA Agonists Administration and Dosage
          Hypnotics and Sedatives Pharmacokinetics
          Insomnia Epidemiology
          Multicenter Studies
          Placebos
          Questionnaires
          Random Assignment
      ab: A number of clinical approaches are utilized in managing insomnia. Indipion (Pfizer) is a selective non-benzodiazepine sedative hypnotic under consideration by FDA for the treatment of insomnia. Like other agents in its class, indiplon binds selectively to the GABA-A receptors in the brain, promoting sleep. Clinical studies have demonstrated improved efficacy in the treatment of sleep initiation and sleep maintenance with indipton therapy in patients with acute and chronic insomnia.
      pubtype: Academic Journal
      doctype:
        tables/charts
        Journal Article
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    language: English
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