Focus on... indiplon: a short-acting GABA-A receptor agonist sedative hypnotic for the treatment of insomnia.

A number of clinical approaches are utilized in managing insomnia. Indipion (Pfizer) is a selective non-benzodiazepine sedative hypnotic under consideration by FDA for the treatment of insomnia. Like other agents in its class, indiplon binds selectively to the GABA-A receptors in the brain, promotin...

Full description

Bibliographic Details
Published in:Formulary Vol. 41; no. 7; pp. 316 - 321
Main Authors: Gryskiewicz KA, Semanco M
Format: tables/charts Journal Article
Published: MJH Life Sciences Jul2006
Online Access:View this record in EBSCOhost
Description
Summary:A number of clinical approaches are utilized in managing insomnia. Indipion (Pfizer) is a selective non-benzodiazepine sedative hypnotic under consideration by FDA for the treatment of insomnia. Like other agents in its class, indiplon binds selectively to the GABA-A receptors in the brain, promoting sleep. Clinical studies have demonstrated improved efficacy in the treatment of sleep initiation and sleep maintenance with indipton therapy in patients with acute and chronic insomnia.