Oral immunization of mice with lactic acid bacteria producing Helicobacter pylori urease B subunit partially protects against challenge with Helicobacter felis.

BACKGROUND: The development of an efficacious vaccine against infection with Helicobacter pylori, the causative agent of chronic gastritis, peptic ulcer disease, and gastric adenocarcinoma, remains a challenge. Since the use of mucosal adjuvants is limited in human application, we have evaluated the...

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Publicado en:Journal of Infectious Diseases Vol. 192; no. 8; pp. 1441 - 1450
Autores principales: Corthésy B, Boris S, Isler P, Grangette C, Mercenier A
Formato: pictorial research tables/charts Journal Article
Publicado: Oxford University Press / USA 10/15/2005
Acceso en línea:Ver este registro en EBSCOhost