The effect of alagebrium chloride (ALT-711), a novel glucose cross-link breaker, in the treatment of elderly patients with diastolic heart failure.

Background: Despite its high prevalence, optimal therapy for diastolic heart failure (DHF) has not been determined. Alagebrium chloride (ALT-711) is a novel compound that breaks glucose crosslinks and may improve ventricular and arterial compliance.Methods and Results: A total of 23 patients, mean a...

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Bibliographic Details
Published in:Journal of Cardiac Failure Vol. 11; no. 3; pp. 191 - 196
Main Authors: Little WC, Zile MR, Kitzman DW, Hundley WG, O'Brien TX, Degroof RC, Little, William C, Zile, Michael R, Kitzman, Dalane W, Hundley, W Gregory, O'Brien, Terrence X, Degroof, Robert C
Format: diagnostic images pictorial research tables/charts Journal Article
Published: W B Saunders 2005 Apr
Online Access:View this record in EBSCOhost