Speech-evoked neurophysiologic responses in children with learning problems: development and behavioral correlates of perception.

Objectives: To evaluate the maturational progression of speech-evoked P1/N1/N2 cortical responses over the life span, determine whether responses are distinctive in clinical populations experiencing learning problems and elucidate the functional significance of these responses.Design: The P1/N1/N2 c...

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Publicado en:Ear & Hearing (01960202) Vol. 21; no. 6; pp. 554 - 569
Autores principales: Cunningham J, Nicol T, Zecker S, Kraus N, Cunningham, J, Nicol, T, Zecker, S, Kraus, N
Formato: research tables/charts tracings Journal Article
Publicado: Lippincott Williams & Wilkins 2000 Dec
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2000 Dec
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        atl: Speech-evoked neurophysiologic responses in children with learning problems: development and behavioral correlates of perception.
      aug:
        au:
          Cunningham J
          Nicol T
          Zecker S
          Kraus N
          Cunningham, J
          Nicol, T
          Zecker, S
          Kraus, N
        affil: Communication Sciences and Disorders, Northwestern University, Evanston, Illinois 60208, USA
      sug:
        subj:
          Speech Perception In Infancy and Childhood
          Language Development In Infancy and Childhood
          Evoked Potentials, Auditory In Infancy and Childhood
          Speech Discrimination Tests
          Learning Disorders In Infancy and Childhood
          Attention Deficit Hyperactivity Disorder In Infancy and Childhood
          Funding Source
          Comparative Studies
          Acoustic Stimulation
          Questionnaires
          Listening
          Reading
          Spelling
          Neuropsychological Tests
          Language Tests
          Intelligence Tests
          One-Way Analysis of Variance
          Descriptive Statistics
          Pearson's Correlation Coefficient
          Paired T-Tests
          Discriminant Analysis
          Waveforms
          Sex Factors
          Age Factors
          Male
          Female
          Child
          Adolescence
          Adult
          Middle Age
          Aged
          Human
          Child: 6-12 years
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Objectives: To evaluate the maturational progression of speech-evoked P1/N1/N2 cortical responses over the life span, determine whether responses are distinctive in clinical populations experiencing learning problems and elucidate the functional significance of these responses.Design: The P1/N1/N2 complex was measured in 150 normal subjects (5 to 78 yr) and 86 subjects with learning problems (LP) (8 to 15 yr) to a synthetic CV syllable. Analyses included description and comparison of the developmental time course in both groups and evaluation of the relationship between P1/N1/N2 and children's performance on speech discrimination tasks and standardized learning measures.Results: Findings revealed significant changes in waveform morphology, latency and amplitude as a function of age. Maturational patterns in the group of children with learning problems did not differ from the normal group. P1/N1/N2 parameters were significantly correlated with standardized tests of Spelling, Auditory Processing and Listening Comprehension in the LP group. Moreover, there was a predictive relationship between Auditory Processing and N2 latency.Conclusions: The P1/N1/N2 complex changes throughout life from school-age to old age. The developmental sequence throughout the school-age years is similar in normal and LP children. Thus, differences in the rate of P1/Nl/N2 latency and amplitude development do not appear to be distinctive in these two populations. The relationship between P1/N1/N2 parameters and standardized measures of learning (particularly between Auditory Processing and N2 latency) provides new information about the role of these responses in hearing and highlights the potential value in characterizing auditory processing deficits.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        tracings
        Journal Article
      ougenre: Article
    language: English
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