Differentially Addressable Cavities within Metal-Organic Cage-Cross-Linked Polymeric Hydrogels.
Here we report a new class of hydrogels formed by polymers that are cross-linked through subcomponent self-assembled metal-organic cages. Selective encapsulation of guest molecules within the cages creates two distinct internal phases within the hydrogel, which allows for contrasting release profile...
| Published in: | Journal of the American Chemical Society Vol. 137; no. 30; pp. 9722 - 9730 |
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| Main Authors: | , , , , , , |
| Format: | Article |
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American Chemical Society
8/5/2015
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| Subjects: | |
| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=hlh&AN=108979691&site=ehost-live header: @attributes: shortDbName: hlh uiTerm: 108979691 longDbName: Humanities International Complete uiTag: AN controlInfo: bkinfo: jinfo: jid: 00027863 ACS jtl: Journal of the American Chemical Society issn: 00027863 maglogo: N pubinfo: dt: 8/5/2015 vid: 137 iid: 30 pid: 997 pub: American Chemical Society artinfo: ui: 108979691 10.1021/jacs.5b05507 ppf: 9722 ppct: 8 formats: tig: atl: Differentially Addressable Cavities within Metal-Organic Cage-Cross-Linked Polymeric Hydrogels. aug: au: Foster, Jonathan A. Parker, Richard M. Belenguer, Ana M. Norifumi Kishi Sutton, Sam Abell, Chris Nitschke, Jonathan R. affil: University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, United Kingdom Chemical Resources Laboratory, Tokyo Institute of Technology, 4259 Nagatuta, Midori-ku, Yokohama 226-8502, Japan su: Hydrogels Metal-organic frameworks Polymer colloids Structural frames Aldehydes sug: subj: Hydrogels Metal-organic frameworks Polymer colloids Structural frames Aldehydes ab: Here we report a new class of hydrogels formed by polymers that are cross-linked through subcomponent self-assembled metal-organic cages. Selective encapsulation of guest molecules within the cages creates two distinct internal phases within the hydrogel, which allows for contrasting release profiles of related molecules depending on their aptitude for encapsulation within the cages. The hydrogels were fabricated into microparticles via a droplet-based microfluidic approach and proved responsive to a variety of stimuli, including acid and competing amine or aldehyde subcomponents, allowing for the triggered release of cargo. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y dt: @attributes: year: 2015 holdings: @attributes: islocal: N |
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