Isolation and Molecular Characterization of Brucella Isolates in Cattle Milk in Uganda.

Brucellosis is endemic in livestock and humans in Uganda and its transmission involves a multitude of risk factors like consumption of milk from infected cattle. To shed new light on the epidemiology of brucellosis in Uganda the present study used phenotypic and molecular approaches to delineate the...

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Publicado en:BioMed Research International Vol. 2015; pp. 1 - 10
Autores principales: Mugizi, Denis Rwabiita, Muradrasoli, Shaman, Boqvist, Sofia, Erume, Joseph, Nasinyama, George William, Waiswa, Charles, Mboowa, Gerald, Klint, Markus, Magnusson, Ulf
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 2/22/2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2/22/2015
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      pub: Wiley-Blackwell
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        10.1155/2015/720413
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        atl: Isolation and Molecular Characterization of Brucella Isolates in Cattle Milk in Uganda.
      aug:
        au:
          Mugizi, Denis Rwabiita
          Muradrasoli, Shaman
          Boqvist, Sofia
          Erume, Joseph
          Nasinyama, George William
          Waiswa, Charles
          Mboowa, Gerald
          Klint, Markus
          Magnusson, Ulf
        affil: College of Veterinary Medicine, Animal Resources and Bio-Security, Makerere University, P.O. Box 7062, Kampala, Uganda
      sug:
        subj:
          Cattle
          Milk Analysis
          Brucellosis Etiology
          Genotype
          Phenotype
          Molecular Biology Methods
          Uganda
          DNA Analysis
          Polymerase Chain Reaction
          Descriptive Statistics
          Electrophoresis, Agar Gel
          Sequence Analysis
          Bacterial Typing Techniques
          Funding Source
      ab: Brucellosis is endemic in livestock and humans in Uganda and its transmission involves a multitude of risk factors like consumption of milk from infected cattle. To shed new light on the epidemiology of brucellosis in Uganda the present study used phenotypic and molecular approaches to delineate the Brucella species, biovars, and genotypes shed in cattle milk. Brucella abortus without a biovar designation was isolated from eleven out of 207 milk samples from cattle in Uganda. These isolates had a genomic monomorphism at 16 variable number tandem repeat (VNTR) loci and showed in turn high levels of genetic variation when compared with other African strains or other B. abortus biovars from other parts of the world. This study further highlights the usefulness of MLVA as an epidemiological tool for investigation of Brucella infections.
      pubtype: Academic Journal
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    language: English
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