RLN2 Is a Positive Regulator of AKT-2-Induced Gene Expression Required for Osteosarcoma Cells Invasion and Chemoresistance.

The aim of the study was to determine the effect of H2 relaxin (RLN2) on invasion, migration, and chemosensitivity to cisplatin in human osteosarcoma U2-OS and MG-63 cells and then to investigate the effect of RLN2 on the AKT/NF-κB signaling pathway. The expression of RLN2, p-AKT (Ser473), and p-ERK...

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Detalles Bibliográficos
Publicado en:BioMed Research International Vol. 2015; pp. 1 - 13
Autores principales: Ma, Jinfeng, Huang, Hai, Han, Zenggang, Zhu, Changzheng, Yue, Bin
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 7/2/2015
Acceso en línea:Ver este registro en EBSCOhost