Preclinical imaging evaluation of novel TSPO-PET ligand 2-(5,7-Diethyl-2-(4-(2-[(18)F]fluoroethoxy)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide ([ (18)F]VUIIS1008) in glioma.
Purpose: Translocator protein (TSPO) concentrations are elevated in glioma, suggesting a role for TSPO positron emission tomography (PET) imaging in this setting. In preclinical PET studies, we evaluated a novel, high-affinity TSPO PET ligand, [(18)F]VUIIS1008, in healthy mice and glioma-bearing rat...
| Published in: | Molecular Imaging & Biology Vol. 16; no. 6; pp. 813 - 821 |
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| Main Authors: | , , , , |
| Format: | research Journal Article |
| Published: |
Springer Nature
Dec2014
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| Online Access: | View this record in EBSCOhost |