A Genetic Algorithm Based Support Vector Machine Model for Blood-Brain Barrier Penetration Prediction.

Blood-brain barrier (BBB) is a highly complex physical barrier determining what substances are allowed to enter the brain. Support vector machine (SVM) is a kernel-based machine learning method that is widely used in QSAR study. For a successful SVM model, the kernel parameters for SVM and feature s...

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Bibliographic Details
Published in:BioMed Research International Vol. 2015; pp. 1 - 14
Main Authors: Zhang, Daqing, Xiao, Jianfeng, Zhou, Nannan, Zheng, Mingyue, Luo, Xiaomin, Jiang, Hualiang, Chen, Kaixian
Format: Journal Article
Published: Wiley-Blackwell 10/4/2015
Online Access:View this record in EBSCOhost