Very preterm adolescents show impaired performance with increasing demands in executive function tasks.

Background: Very preterm birth is often associated with executive function deficits later in life. The transition to adolescence increases personal autonomy, independence and, in parallel, the demands placed on executive functions at home and in school.Aim: To assess the impact of increasing demands...

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Publicado en:Early Human Development Vol. 92; pp. 37 - 44
Autores principales: Wehrle, Flavia M., Kaufmann, Liane, Benz, Laura D., Huber, Reto, O'Gorman, Ruth L., Latal, Beatrice, Hagmann, Cornelia F., O'Gorman, Ruth L
Formato: research Journal Article
Publicado: Elsevier B.V. Jan2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2016
      vid: 92
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      pub: Elsevier B.V.
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        111877203
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        NLM26651084
        111877203
        10.1016/j.earlhumdev.2015.10.021
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        111877203
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        atl: Very preterm adolescents show impaired performance with increasing demands in executive function tasks.
      aug:
        au:
          Wehrle, Flavia M.
          Kaufmann, Liane
          Benz, Laura D.
          Huber, Reto
          O'Gorman, Ruth L.
          Latal, Beatrice
          Hagmann, Cornelia F.
          O'Gorman, Ruth L
        affil: Department of Neonatology, University Hospital Zurich, Switzerland
      sug:
        subj:
          Infant, Premature
          Adolescent Development
          Executive Function
          Female
          Case Control Studies
          Activities of Daily Living
          Adolescence
          Memory, Short Term
          Motor Skills
          Male
          Infant, Newborn
          Child
          Human
          Adolescent: 13-18 years
          Infant, Newborn: birth-1 month
          Child: 6-12 years
          Female
          Male
      ab: Background: Very preterm birth is often associated with executive function deficits later in life. The transition to adolescence increases personal autonomy, independence and, in parallel, the demands placed on executive functions at home and in school.Aim: To assess the impact of increasing demands on executive function performance in very preterm children and adolescents with normal intellectual and motor functions.Methods: Forty-one very preterm children and adolescents with normal intellectual and motor functions and 43 healthy term-born peers were assessed at a mean age of 13.0 years (SD: 1.9; range: 10.0-16.9). A comprehensive battery of performance-based executive function measures with different demand levels as well as a parent-rating questionnaire evaluating executive functions relevant for everyday life was applied. Standardized mean differences between groups of d ≥ .41 were regarded as clinically relevant.Results: No group differences were found at the lowest demand levels of working memory (d=.09), planning (d=-.01), cognitive flexibility (d=-.21) and verbal fluency (d=-.14) tasks, but very preterm participants scored significantly below their term-born peers in the most demanding levels (d=-.50, -.59, -.43 and -.55, respectively). These differences were clinically relevant. Executive functions relevant for everyday life were strongly impaired in very preterm participants, e.g., global executive composite (d=-.66).Conclusion: Very preterm children and adolescents with normal intellectual and motor functions are at high risk for executive function deficits that may only become apparent with increasing demands, potentially leading to academic and other deficits.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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