Dearomative Indole (3 + 2) Reactions with Azaoxyallyl Cations -- New Method for the Synthesis of Pyrroloindolines.

Herein, we report the first examples of the synthesis of pyrroloindolines by means of (3 + 2) dearomative annulation reactions between 3-substituted indoles and highly reactive azaoxyallyl cations. Computational studies using density functional theory (DFT) (B3LYP-D3/6-311G**++) support a stepwise r...

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Bibliographic Details

Published in:	Journal of the American Chemical Society Vol. 137; no. 47; pp. 14861 - 14865
Main Authors:	DiPoto, Maria C., Hughes, Russell P., Wu, Jimmy
Format:	Article
Published:	American Chemical Society 12/2/2015
Subjects:	Indoline Cations Annulation Density functional theory Carbon-carbon bonds
Online Access:	View this record in EBSCOhost