Comparison of Prooxidant-Antioxidant Balance between the Hospitalized Patients and the Healthy Subjects.
Objective: In this study we aimed to evaluate the prooxidant-antioxidant balance (PAB) in the hospitalized patients in comparison with healthy subjects. Setting: This cross sectional study was done from 2010 to 2012 in Mashhad University of Medical Sciences teaching hospitals. Methods: The PAB assay...
| Publicado en: | International Medical Journal Vol. 22; no. 6; pp. 517 - 521 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Japan International Cultural Exchange Foundation
Dec2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=112004976&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 112004976 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13412051 23J1 jtl: International Medical Journal issn: 13412051 maglogo: N pubinfo: dt: Dec2015 vid: 22 iid: 6 pid: 29386 pub: Japan International Cultural Exchange Foundation artinfo: ui: 112004976 112004976 112004976 112004976 ppf: 517 ppct: 4 formats: fmt: @attributes: type: P tig: atl: Comparison of Prooxidant-Antioxidant Balance between the Hospitalized Patients and the Healthy Subjects. aug: au: Nouri, Masoumeh Sadeghian, Reihaneh Nematy, Mohsen Hosseini, Golkoo Mostafavi-Toroghi, Hesam Tavallaie, Shima Ghayour-Mobarhan, Majid affil: Biochemistry of Nutrition Research Center, Faculty of Medicine, Mashhad University of Medical Sciences Mashhad, Iran sug: subj: Antioxidants Inpatients Hospitalization Patient Selection Nutrition Homeostasis Physiology Free Radicals Oxidation-Reduction Physiology Patient Admission Control Group Anthropometry Data Collection Oxidative Stress Adolescence Reactive Oxygen Species Male Female Adult Smoking Systolic Pressure Diastolic Pressure Blood Chemical Analysis Data Analysis Software Descriptive Statistics Mann-Whitney U Test Albumins C-Reactive Protein Blood Human Adolescent: 13-18 years Adult: 19-44 years Male Female ab: Objective: In this study we aimed to evaluate the prooxidant-antioxidant balance (PAB) in the hospitalized patients in comparison with healthy subjects. Setting: This cross sectional study was done from 2010 to 2012 in Mashhad University of Medical Sciences teaching hospitals. Methods: The PAB assay, which is used in this study, measures the prooxidant burden and the antioxidant capacity simultaneously in one assay, thereby calculating a measure of redox status. One hundred seventy four patients who were admitted to the hospital, and 171 age and sex-matched healthy subjects were recruited to the study as case and control groups respectively. Anthropometric characteristics, biochemical parameters, prooxidant-antioxidant balance and serum high-sensitivity C-reactive protein (hs-CRP) were assessed in both groups. Statistical analysis was then preformed on the data. Results: PAB values were significantly higher in case group as compared with the control group (P < 0.05). No significant correlation was observed in age, body mass index and hip circumference with serum PAB values PAB values in either group. Also serum levels of the albumin, pre-albumin, and hs-CRP showed no significant correlation with PAB values in the patient group (P < 0.05). Conclusion: Being assessed by PAB assay, hospitalized patients demonstrated significant higher prooxidant antioxidant balance, as compared with the healthy subjects. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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