Biodistribution Study of Intravenously Injected Cetuximab-IRDye700DX in Cynomolgus Macaques.

Purpose: The use of receptor-targeted antibodies conjugated to photosensitizers is actively being explored to enhance treatment efficacy. To facilitate clinical testing, we evaluated cetuximab conjugated to IRDye700DX (IR700) in cynomolgus macaques.Procedures: Total IR700 and intact cetuximab-IR700...

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Publicado en:	Molecular Imaging & Biology Vol. 18; no. 2; pp. 232 - 243
Autores principales:	Boer, E., Samuel, S., French, D., Warram, J., Schoeb, T., Rosenthal, E., Zinn, K., de Boer, E, French, D N, Warram, J M, Schoeb, T R, Rosenthal, E L, Zinn, K R
Formato:	research Journal Article
Publicado:	Springer Nature Apr2016
Acceso en línea:	Ver este registro en EBSCOhost